Energy drinks leading to infertility by causing cytotoxic injury of the ovaries - A randomized controlled animal trial
نویسندگان
چکیده
Aim: To observe energy drink induced ovarian cytotoxicity and possible protective effects of co-administration omega 3 fatty acids. Methods: The experimental study comprised 36 adult female albino rats was conducted at anatomy department, PGMI, Lahore. Animals were divided into groups. Group A control. Groups B received drink. C along with drinks once daily orally for 30 consecutive days. Rats sacrificed under deep anesthesia on 30th day. Ovaries extracted sections stained H&E stains. Results analyzed using SPSS. p-value < 0.05 considered statistically significant. Results: administered showed marked pyknosis graafian follicular cells oocyte nuclei when compared control dink plus treated animals. Vacuolization the also more pronounced in group (p <0.001). Ovarian stroma vascular congestion tissue infiltration as to groups.. Conclusion: Oxidative stress by is basic cause behind toxic change seen histo-architecture. Omega-3 significantly decreased these detrimental due its antioxidant anti-inflammatory action. This can be a pioneer guiding population about harmful morphology, leading ultimately infertility. Keywords: Energy drinks; Omega-3; Cytotoxicity; stress; Carbonated Beverages; Infertility; Caffeine
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ژورنال
عنوان ژورنال: Pakistan Journal of Medical and Health Sciences
سال: 2021
ISSN: ['1996-7195']
DOI: https://doi.org/10.53350/pjmhs2115112862